Advanced visual research is involved in the study of the dependencies of visual response on the distribution of adapting luminance across the visual field. In this work, two different street lighting adaptation conditions were applied by having the subjects to adapt to different background images in a laboratory setting. The difference in the background images is that one includes street luminaires and other light spots, whereas the other does not. Ten subjects (mean age 30 years) participated in the experiment. The subjects were asked to indicate the detection of targets appearing at different eccentricities (from –750 to 750). The results indicate that the high luminance objects affect peripheral target detection in mesopic lighting conditions. Contrast threshold values for the targets close to high luminance objects and in the periphery (200, 300,450 and 600) with non-uniform surroundings were decreased in the background without street luminaires and other light spots.