РУсскоязычный Архив Электронных СТатей периодических изданий
Вестник Московского университета. Серия 23. Антропология./2014/№ 3/

Genome diversity and evolution history of ethnic groups from European Russia and Sub-Arctic Transuralic region

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120 Section MOLECULAR ANTHROPOLOGY – NEW ADVANCES GENOME DIVERSITY AND EVOLUTION HISTORY OF ETHNIC GROUPS FROM EUROPEAN RUSSIA AND SUB-ARCTIC TRANSURALIC REGION Limborska S.1 , Khrunin A.1 Rabinovich V.3 1 , Khokhrin D.1 , Verbenko D.1 , Gerasimova D.2 Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, Russia 2Ugra State University, Khanty-Mansiisk, Russia 3Ugra Research Institute of Cellular Technology with Stem Cell Bank, Khanty-Mansiisk, Russia Understanding the genetic structure of the European population is very important from historical and anthropological points of view. <...> Several studies have examined the fi ne-scale structure of human genetic variation in Europe. <...> But populations of Northern-Eastern European area and Sub-Arctic Transuralic region are less investigated. <...> These territories are inhabited by different indigenous Finno-Ugric peoples and ethnic Russians. <...> To explore genetic structure of the region we analyzed single nucleotide polymorphisms using different versions of Illumina BeadChips. <...> Principal components (PC) analysis, ADMIXTURE clustering and Wright’s fi xation indices (FST) were used to examine population structure of Khanty, Mansi, Komi, Veps and Russians. <...> Mansi were indigenous inhabitants of Northern European area prior to 17th Century AD. <...> This ethnic group undergone trans-Uralic migration and nowadays inhabits Sub-Arctic Region of Western Siberia. <...> The Khanty, closely related to Mansi by linguistic classifi cation, are the indigenous inhabitants of this region. <...> Both the Mansi and the Khanty peoples have genomic characteristics that differentiated them from all others. <...> Komi are also inhabitants of the territory at Northern-Eastern Europe. <...> They formed two neighbored clusters at PC plot. <...> The Veps are the Finno-Ugric minority that is one of the oldest people of northern Europe. <...> Veps gene pool reveals similarity with Finns and Komi. <...> Russians are the most abundant people in Northern-Eastern Europe. <...> Principal component analysis showed signifi cant differences between Russians of Northern European region and Russian populations from the central part of Russian Plain. <...> The later Russian populations formed a single cluster on PC plot. <...> In contrast, Northern Russians demonstrated close relationships with Finno-Ugric populations. <...> The results obtained demonstrate <...>
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