РУсскоязычный Архив Электронных СТатей периодических изданий
Педиатрическая фармакология/2016/№ 2/

FROM THE INTERNATIONAL LITERATURE

The use and effectiveness of probiotics in children has been a long lasting important debate during the GENETIC ANALYSIS OF CHILDREN WITH CONGENITAL past years, which continues to raise the attention of TUFTING ENTEROPATHY (CTE). A CLINICAL CONDITION pediatricans. In particular, several articles in the recent CARACHTERIZED BY DIARRHEA past have discussed the role of probiotics for the pre- • Congenital tufting enteropathy (CTE), an inherited autovention of Antibiotic-Associated Diarrhea in children, somal recessive rare disease, is a severe diarrhea of focusing on advantages and disadvantages.

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rest to the paediatricians in attendance, therefore, we have selected highlights of the summit which are relevant to child health. <...> FROM THE INTERNATIONAL LITERATURE THE ROLE OF PROBIOTICS IN THE ANTIBIOTIC ASSOCIATED DIARROHEA IN CHILDREN 180 • The use and effectiveness of probiotics in children has been a long lasting important debate during the past years, which continues to raise the attention of pediatricans. <...> In particular, several articles in the recent past have discussed the role of probiotics for the prevention of Antibiotic-Associated Diarrhea in children, focusing on advantages and disadvantages. <...> A paper published by the ESPGHAN Working Group for Probiotics Prebiotics in the Journal of Pediatric Gastroenterology and Nutrition in December 2015 (http://www.ncbi. nlm.nih.gov/pubmed/26756877) provides recommendations, developed by the Working Group (WG) on Probiotics of ESPGHAN, for the use of probiotics for the prevention of antibiotic-associated diarrhea (AAD) in children. <...> The recommendations were based on a systematic review of previously completed systematic reviews and of randomized controlled trials (RCTs) published subsequently to these reviews. <...> The use of probiotics for preventing AAD was considered in particular in the presence of risk factors such as class of antibiotic (s), duration of antibiotic treatment, age, need for hospitalization, comorbidities, or previous episodes of AAD diarrhea. <...> Szajewska H, Canani RB, Guarino A, Hojsak I, Indrio F, Kolacek S, Orel R, Shamir R, Vandenplas Y, van Goudoever JB, Weizman Z. Probiotics for the Prevention of Antibiotic-Associated Diarrhea in Children. <...> Dec. 2015, Epub ahead of print (http://www.ncbi.nlm.nih.gov/pubmed/26756877) • A further recent report from a working group of gastroenterologists and nutritionists from the Great Ormond Street Hospital (UK), the Guy’s and St Thomas NHS Foundation Trust (UK), the University St Joan de Resus (Sp), and the University of Nottingham UK, discusses the role of antibiotic resistance, and the background and prevalence of Antibiotic Associated Diarrhoea (AAD). <...> The working group emphasizes that following an increasing amount of interest in therapies that may influence changes to gut microbiota, an approach that has been adopted by many healthcare professionals for the management of AAD is the use of probioticis. <...> The report discusses the evidences reported in several studies, that the use of specific probiotics effectively reduces the incidence of AAD in children, also reduce associated healthcare costs and aid antibiotic compliance. <...> REPORT 2015 (http://paediatricgutmicrobiota.com/aadeng <...>
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