FROM THE INTERNATIONAL LITERATURE
The use and effectiveness of probiotics in children has been a long lasting important debate during the GENETIC ANALYSIS OF CHILDREN WITH CONGENITAL past years, which continues to raise the attention of TUFTING ENTEROPATHY (CTE). A CLINICAL CONDITION pediatricans. In particular, several articles in the recent CARACHTERIZED BY DIARRHEA past have discussed the role of probiotics for the pre- • Congenital tufting enteropathy (CTE), an inherited autovention of Antibiotic-Associated Diarrhea in children, somal recessive rare disease, is a severe diarrhea of focusing on advantages and disadvantages.
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rest to the paediatricians in attendance, therefore, we have
selected highlights of the summit which are relevant to child
health. <...> FROM THE INTERNATIONAL LITERATURE
THE ROLE OF PROBIOTICS IN THE ANTIBIOTIC
ASSOCIATED DIARROHEA IN CHILDREN
180
• The use and effectiveness of probiotics in children
has been a long lasting important debate during the
past years, which continues to raise the attention of
pediatricans. <...> In particular, several articles in the recent
past have discussed the role of probiotics for the prevention
of Antibiotic-Associated Diarrhea in children,
focusing on advantages and disadvantages. <...> A paper
published by the ESPGHAN Working Group for Probiotics
Prebiotics in the Journal of Pediatric Gastroenterology
and Nutrition in December 2015 (http://www.ncbi.
nlm.nih.gov/pubmed/26756877) provides recommendations,
developed by the Working Group (WG) on
Probiotics of ESPGHAN, for the use of probiotics for
the prevention of antibiotic-associated diarrhea (AAD)
in children. <...> The recommendations were based on a
systematic review of previously completed systematic
reviews and of randomized controlled trials (RCTs)
published subsequently to these reviews. <...> The
use of probiotics for preventing AAD was considered in
particular in the presence of risk factors such as class of
antibiotic (s), duration of antibiotic treatment, age, need
for hospitalization, comorbidities, or previous episodes
of AAD diarrhea. <...> Szajewska H, Canani RB, Guarino A, Hojsak I, Indrio F,
Kolacek S, Orel R, Shamir R, Vandenplas Y, van
Goudoever JB, Weizman Z. Probiotics for the Prevention
of Antibiotic-Associated Diarrhea in Children. <...> Dec. 2015, Epub ahead of print
(http://www.ncbi.nlm.nih.gov/pubmed/26756877)
• A further recent report from a working group of gastroenterologists
and nutritionists from the Great Ormond Street
Hospital (UK), the Guy’s and St Thomas NHS Foundation
Trust (UK), the University St Joan de Resus (Sp), and the
University of Nottingham UK, discusses the role of antibiotic
resistance, and the background and prevalence
of Antibiotic Associated Diarrhoea (AAD). <...> The working
group emphasizes that following an increasing amount
of interest in therapies that may influence changes to
gut microbiota, an approach that has been adopted by
many healthcare professionals for the management of
AAD is the use of probioticis. <...> The report discusses the
evidences reported in several studies, that the use of
specific probiotics effectively reduces the incidence of
AAD in children, also reduce associated healthcare costs
and aid antibiotic compliance. <...> REPORT 2015
(http://paediatricgutmicrobiota.com/aadeng <...>
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